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Integrin signaling downregulates filopodia during muscle–tendon attachment

Cells need to sense their environment to ensure accurate targeting to specific destinations. This occurs in developing muscles, which need to attach to tendon cells before muscle contractions can begin. Elongating myotube tips form filopodia, which are presumed to have sensory roles, and are later s...

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Bibliographic Details
Published in:J Cell Sci
Main Authors: Richier, Benjamin, Inoue, Yoshiko, Dobramysl, Ulrich, Friedlander, Jonathan, Brown, Nicholas H., Gallop, Jennifer L.
Format: Artigo
Language:Inglês
Published: The Company of Biologists Ltd 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6127725/
https://ncbi.nlm.nih.gov/pubmed/30054384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.217133
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