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Integrin signaling downregulates filopodia during muscle–tendon attachment

Cells need to sense their environment to ensure accurate targeting to specific destinations. This occurs in developing muscles, which need to attach to tendon cells before muscle contractions can begin. Elongating myotube tips form filopodia, which are presumed to have sensory roles, and are later s...

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Библиографические подробности
Опубликовано в: :J Cell Sci
Главные авторы: Richier, Benjamin, Inoue, Yoshiko, Dobramysl, Ulrich, Friedlander, Jonathan, Brown, Nicholas H., Gallop, Jennifer L.
Формат: Artigo
Язык:Inglês
Опубликовано: The Company of Biologists Ltd 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6127725/
https://ncbi.nlm.nih.gov/pubmed/30054384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.217133
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