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Computer Simulations Predict High Structural Heterogeneity of Functional State of NMDA Receptors

N-methyl-D-aspartate receptors (NMDARs)—i.e., transmembrane proteins expressed in neurons—play a central role in the molecular mechanisms of learning and memory formation. It is unclear how the known atomic structures of NMDARs determined by x-ray crystallography and electron cryomicroscopy (18 publ...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biophys J
Hauptverfasser: Sinitskiy, Anton V., Pande, Vijay S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6127453/
https://ncbi.nlm.nih.gov/pubmed/30029773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.06.023
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