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Novel properties of recombinant Sso7d-Taq DNA polymerase purified using aqueous two-phase extraction: Utilities of the enzyme in viral diagnosis

Using Sso7d from Sulfolobus solfataricus as the DNA binding protein fused to Taq DNA polymerase at its amino terminus, we report the hyper-expression and a novel purification methodology of Sso7d-Taq polymerase (S-Taq) using aqueous two-phase extraction system followed by Ni-affinity chromatography....

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Bibliografiske detaljer
Udgivet i:Biotechnol Rep (Amst)
Main Authors: Sundarrajan, Sudarson, Parambath, Sreesada, Suresh, Swetha, Rao, Sneha, Padmanabhan, Sriram
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6127375/
https://ncbi.nlm.nih.gov/pubmed/30197870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.btre.2018.e00270
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