Reduced expression of stearoyl-CoA desaturase-1, but not free fatty acid receptor 2 or 4 in subcutaneous adipose tissue of patients with newly diagnosed type 2 diabetes mellitus

BACKGROUND: In subcutaneous adipose tissue (SAT), higher stearoyl-CoA desaturase-1 (SCD1) expression has been related to improved insulin sensitivity in thiazolidinedione-treated type 2 diabetes mellitus patients. In animal models, deficiency of the free fatty acid receptor (FFAR) 2 associated with...

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Detalhes bibliográficos
Publicado no:Nutr Diabetes
Main Authors: Bódis, Kálmán, Kahl, Sabine, Simon, Marie-Christine, Zhou, Zhou, Sell, Henrike, Knebel, Birgit, Tura, Andrea, Strassburger, Klaus, Burkart, Volker, Müssig, Karsten, Markgraf, Daniel, Al-Hasani, Hadi, Szendroedi, Julia, Roden, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6127327/
https://ncbi.nlm.nih.gov/pubmed/30190473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41387-018-0054-9
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