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Cardiosphere-derived cells suppress allogeneic lymphocytes by production of PGE2 acting via the EP4 receptor

Cardiosphere-derived cells (CDCs) are a cardiac progenitor cell population, which have been shown to possess cardiac regenerative properties and can improve heart function in a variety of cardiac diseases. Studies in large animal models have predominantly focussed on using autologous cells for safet...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Dutton, Luke C., Dudhia, Jayesh, Catchpole, Brian, Hodgkiss-Geere, Hannah, Werling, Dirk, Connolly, David J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6127326/
https://ncbi.nlm.nih.gov/pubmed/30190508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-31569-1
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