Mouse Mast Cell Protease 4 Deletion Protects Heart Function and Survival After Permanent Myocardial Infarction

Chymase, a mast cell serine protease involved in the generation of multiple cardiovascular factors, such as angiotensin II and endothelin-1 (ET-1), is elevated and participates in tissue degeneration after permanent myocardial infarction (PMI). Anesthetized 4-month old male wild-type (WT) C57BL/6J m...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Houde, Martin, Schwertani, Adel, Touil, Hanène, Desbiens, Louisane, Sarrhini, Otman, Lecomte, Roger, Lepage, Martin, Gagnon, Hugo, Takai, Shinji, Pejler, Gunnar, Jacques, Danielle, Gobeil, Fernand, Day, Robert, D’Orléans-Juste, Pedro
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6127244/
https://ncbi.nlm.nih.gov/pubmed/30233357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00868
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