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Sensitive Measurement of Mitophagy by Flow Cytometry Using the pH-dependent Fluorescent Reporter mt-Keima

Mitophagy is a process of selective removal of damaged or unnecessary mitochondria using autophagy machinery. Close links have been found between defective mitophagy and various human diseases, including neurodegenerative diseases, cancer, and metabolic diseases. In addition, recent studies have sho...

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Bibliografske podrobnosti
izdano v:J Vis Exp
Main Authors: Um, Jee-Hyun, Kim, Young Yeon, Finkel, Toren, Yun, Jeanho
Format: Artigo
Jezik:Inglês
Izdano: MyJove Corporation 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6126785/
https://ncbi.nlm.nih.gov/pubmed/30148491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/58099
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