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Control of the Restriction Point by Rb and p21

The Restriction Point was originally defined as the moment that cells commit to the cell cycle and was later suggested to coincide with hyperphosphorylation of the retinoblastoma protein (Rb). Current cell cycle models posit that cells exit mitosis into a pre-Restriction Point state, where they have...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Moser, Justin, Miller, Iain, Carter, Dylan, Spencer, Sabrina L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6126733/
https://ncbi.nlm.nih.gov/pubmed/30111539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1722446115
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