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Phosphopeptide Enrichment Coupled with Label-free Quantitative Mass Spectrometry to Investigate the Phosphoproteome in Prostate Cancer

Phosphoproteomics involves the large-scale study of phosphorylated proteins. Protein phosphorylation is a critical step in many signal transduction pathways and is tightly regulated by kinases and phosphatases. Therefore, characterizing the phosphoproteome may provide insights into identifying novel...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Cheng, Larry C., Li, Zhen, Graeber, Thomas G., Graham, Nicholas A., Drake, Justin M.
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6126612/
https://ncbi.nlm.nih.gov/pubmed/30124664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/57996
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