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Casein kinase 2 mediated phosphorylation of Spt6 modulates histone dynamics and regulates spurious transcription

CK2 is an essential protein kinase implicated in various cellular processes. In this study, we address a potential role of this kinase in chromatin modulations associated with transcription. We found that CK2 depletion from yeast cells leads to replication-independent increase of histone H3K56 acety...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Gouot, Emmanuelle, Bhat, Wajid, Rufiange, Anne, Fournier, Eric, Paquet, Eric, Nourani, Amine
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6125631/
https://ncbi.nlm.nih.gov/pubmed/29905868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky515
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