Population Pharmacokinetics and Cerebrospinal Fluid Penetration of Fluconazole in Adults with Cryptococcal Meningitis

Robust population pharmacokinetic (PK) data for fluconazole are scarce. The variability of fluconazole penetration into the central nervous system (CNS) is not known. A fluconazole PK study was conducted in 43 patients receiving oral fluconazole (usually 800 mg every 24 h [q24h]) in combination with...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Stott, Katharine E., Beardsley, Justin, Kolamunnage-Dona, Ruwanthi, Castelazo, Anahi Santoyo, Kibengo, Freddie Mukasa, Mai, Nguyen Thi Hoang, Tùng, Nguyễn Lê Nhu’, Cuc, Ngo Thi Kim, Day, Jeremy, Hope, William
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6125572/
https://ncbi.nlm.nih.gov/pubmed/29914943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00885-18
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