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Mapping the Interface of a GPCR Dimer: A Structural Model of the A(2A) Adenosine and D(2) Dopamine Receptor Heteromer

The A(2A) adenosine (A(2A)R) and D(2) dopamine (D(2)R) receptors form oligomers in the cell membrane and allosteric interactions across the A(2A)R–D(2)R heteromer represent a target for development of drugs against central nervous system disorders. However, understanding of the molecular determinant...

詳細記述

保存先:
書誌詳細
出版年:Front Pharmacol
主要な著者: Borroto-Escuela, Dasiel O., Rodriguez, David, Romero-Fernandez, Wilber, Kapla, Jon, Jaiteh, Mariama, Ranganathan, Anirudh, Lazarova, Tzvetana, Fuxe, Kjell, Carlsson, Jens
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6125358/
https://ncbi.nlm.nih.gov/pubmed/30214407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00829
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