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Calcium imaging and dynamic causal modelling reveal brain-wide changes in effective connectivity and synaptic dynamics during epileptic seizures

Pathophysiological explanations of epilepsy typically focus on either the micro/mesoscale (e.g. excitation-inhibition imbalance), or on the macroscale (e.g. network architecture). Linking abnormalities across spatial scales remains difficult, partly because of technical limitations in measuring neur...

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Udgivet i:PLoS Comput Biol
Main Authors: Rosch, Richard E., Hunter, Paul R., Baldeweg, Torsten, Friston, Karl J., Meyer, Martin P.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6124808/
https://ncbi.nlm.nih.gov/pubmed/30138336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006375
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