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Clinical utility of fulvestrant in the treatment of breast cancer: a report on the emerging clinical evidence
Fulvestrant is the first selective estrogen receptor (ER) downregulator available in clinical practice. It is a pure antiestrogen with no agonistic effects, leading to degradation of ER alpha, with activity in tamoxifen-resistant breast cancer (BC) models. Pharmacokinetic and pharmacodynamic studies...
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| Publicado no: | Cancer Manag Res |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6124791/ https://ncbi.nlm.nih.gov/pubmed/30214302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S137772 |
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