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Using structural equation modelling to jointly estimate maternal and fetal effects on birthweight in the UK Biobank

BACKGROUND: To date, 60 genetic variants have been robustly associated with birthweight. It is unclear whether these associations represent the effect of an individual’s own genotype on their birthweight, their mother’s genotype, or both. METHODS: We demonstrate how structural equation modelling (SE...

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Detalhes bibliográficos
Publicado no:Int J Epidemiol
Main Authors: Warrington, Nicole M, Freathy, Rachel M, Neale, Michael C, Evans, David M
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6124616/
https://ncbi.nlm.nih.gov/pubmed/29447406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ije/dyy015
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