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Defective BTLA functionality is rescued by restoring lipid metabolism in lupus CD4(+) T cells
Coinhibitory receptors play an important role in the prevention of autoimmune diseases, such as systemic lupus erythematosus (SLE), by limiting T cell activation. B and T lymphocyte attenuator (BTLA) is an inhibitory receptor, similar to cytotoxic T lymphocyte–associated protein 4 (CTLA-4) and progr...
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| I publikationen: | JCI Insight |
|---|---|
| Huvudupphovsmän: | , , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American Society for Clinical Investigation
2018
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6124536/ https://ncbi.nlm.nih.gov/pubmed/29997289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.99711 |
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