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Overview of inactivating mutations in the protein-coding genome of the mouse reference strain C57BL/6J

Mice are extremely important as the premier model organism in human biomedical and mammalian genetic research. The genomes of several tens of mouse inbred strains have been sequenced. They have been compared to the genome of C57BL/6J, considered by convention as the reference genome. Based on a comp...

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Pubblicato in:JCI Insight
Autori principali: Timmermans, Steven, Libert, Claude
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6124530/
https://ncbi.nlm.nih.gov/pubmed/29997285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.121758
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