Gomisin A Suppresses Colorectal Lung Metastasis by Inducing AMPK/p38-Mediated Apoptosis and Decreasing Metastatic Abilities of Colorectal Cancer Cells

Gomisin A (G.A) is a dietary lignan compound from Schisandra chinensis. In this study, the effect of G.A on the proliferation and metastasis of colorectal cancer (CRC) cells was investigated using several CRC cell lines and a lung metastasis mouse model. Both oral and intraperitoneal administration...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Kee, Ji-Ye, Han, Yo-Han, Mun, Jeong-Geon, Park, Seong-Hwan, Jeon, Hee D., Hong, Seung-Heon
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6124511/
https://ncbi.nlm.nih.gov/pubmed/30210348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00986
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