Gomisin A Suppresses Colorectal Lung Metastasis by Inducing AMPK/p38-Mediated Apoptosis and Decreasing Metastatic Abilities of Colorectal Cancer Cells

Gomisin A (G.A) is a dietary lignan compound from Schisandra chinensis. In this study, the effect of G.A on the proliferation and metastasis of colorectal cancer (CRC) cells was investigated using several CRC cell lines and a lung metastasis mouse model. Both oral and intraperitoneal administration...

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Bibliographic Details
Published in:Front Pharmacol
Main Authors: Kee, Ji-Ye, Han, Yo-Han, Mun, Jeong-Geon, Park, Seong-Hwan, Jeon, Hee D., Hong, Seung-Heon
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2018
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6124511/
https://ncbi.nlm.nih.gov/pubmed/30210348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00986
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