Asenapine pharmacokinetics and tolerability in a pediatric population

PURPOSE: This study aimed to characterize the pharmacokinetic (PK) properties, safety, and tolerability of asenapine, and to develop a population PK model in pediatric patients with schizophrenia, bipolar disorder, or other psychiatric disorders. METHODS: Two Phase I multiple ascending-dose studies...

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Vydáno v:Drug Des Devel Ther
Hlavní autoři: Dogterom, Peter, Riesenberg, Robert, de Greef, Rik, Dennie, Justin, Johnson, Martin, Pilla Reddy, Venkatesh, Miltenburg, André MM, Findling, Robert L, Jakate, Abhijeet, Carrothers, Timothy J, Troyer, Matthew D
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2018
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6124477/
https://ncbi.nlm.nih.gov/pubmed/30214156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S171475
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