Modulation of subsets of cardiac B lymphocytes improves cardiac function after acute injury

Despite the long-standing recognition that the immune response to acute myocardial injury contributes to adverse left ventricular (LV) remodeling, it has not been possible to effectively target this clinically. Using 2 different in vivo models of acute myocardial injury, we show that pirfenidone con...

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Bibliographic Details
Published in:JCI Insight
Main Authors: Adamo, Luigi, Staloch, Lora J., Rocha-Resende, Cibele, Matkovich, Scot J., Jiang, Wenlong, Bajpai, Geetika, Weinheimer, Carla J., Kovacs, Attila, Schilling, Joel D., Barger, Philip M., Bhattacharya, Deepta, Mann, Douglas L.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2018
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6124442/
https://ncbi.nlm.nih.gov/pubmed/29875326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.120137
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