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The mutational landscape of recurrent versus nonrecurrent human papillomavirus–related oropharyngeal cancer

BACKGROUND. Human papillomavirus–related (HPV-related) oropharyngeal squamous cell carcinomas (OPSCCs) have an excellent response rate to platinum-based chemoradiotherapy. Genomic differences between primary HPV-related OPSCCs that do or do not recur are unknown. Furthermore, it is unclear if HPV-re...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Harbison, R. Alex, Kubik, Mark, Konnick, Eric Q., Zhang, Qing, Lee, Seok-Geun, Park, Heuijoon, Zhang, Jianan, Carlson, Christopher S., Chen, Chu, Schwartz, Stephen M., Rodriguez, Cristina P., Duvvuri, Umamaheswar, Méndez, Eduardo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6124437/
https://ncbi.nlm.nih.gov/pubmed/30046007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.99327
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