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Complement Regulatory Genetic Mutations in the Setting of Autoimmune Thrombotic Thrombocytopenic Purpura: A Case Series

OBJECTIVE: To explore the benefits of adding eculizumab for the treatment of refractory autoimmune thrombotic thrombocytopenic purpura (iTTP) with complement dysregulation. PATIENTS AND METHODS: From January 1, 2014, through July 1, 2017, we identified patients with iTTP defined by ADAMTS13 (disinte...

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Detalhes bibliográficos
Publicado no:Mayo Clin Proc Innov Qual Outcomes
Main Authors: Atrash, Shebli, Sasapu, Appalanaidu, Pandey, Soumya, Cottler-Fox, Michele, Motwani, Pooja
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6124327/
https://ncbi.nlm.nih.gov/pubmed/30225434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mayocpiqo.2017.11.004
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