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Loss of miR-143 and miR-145 in condyloma acuminatum promotes cellular proliferation and inhibits apoptosis by targeting NRAS

The expression profile of miRNAs and their function in condyloma acuminatum (CA) remains unknown. In this study, we aimed to detect the effects of miR-143 and miR-145, the most downregulated in CA samples using high-throughput sequencing, on cell proliferation and apoptosis, to determine a novel the...

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Publicat a:R Soc Open Sci
Autors principals: Liu, Xiaoyan, Zhang, Yu, Wang, Su, Liu, Guoying, Ruan, Liming
Format: Artigo
Idioma:Inglês
Publicat: The Royal Society 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6124073/
https://ncbi.nlm.nih.gov/pubmed/30225000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsos.172376
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