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Simulation of the nodal flow of mutant embryos with a small number of cilia: comparison of mechanosensing and vesicle transport hypotheses

Left–right (L-R) asymmetry in the body plan is determined by nodal flow in vertebrate embryos. Shinohara et al. (Shinohara K et al. 2012 Nat. Commun. 3, 622 (doi:10.1038/ncomms1624)) used Dpcd and Rfx3 mutant mouse embryos and showed that only a few cilia were sufficient to achieve L-R asymmetry. Ho...

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Detalhes bibliográficos
Publicado no:R Soc Open Sci
Main Authors: Omori, Toshihiro, Winter, Katja, Shinohara, Kyosuke, Hamada, Hiroshi, Ishikawa, Takuji
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society Publishing 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6124027/
https://ncbi.nlm.nih.gov/pubmed/30225054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsos.180601
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