In situ serial crystallography for rapid de novo membrane protein structure determination

De novo membrane protein structure determination is often limited by the availability of large crystals and the difficulties in obtaining accurate diffraction data for experimental phasing. Here we present a method that combines in situ serial crystallography with de novo phasing for fast, efficient...

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Bibliographic Details
Published in:Commun Biol
Main Authors: Huang, Chia-Ying, Olieric, Vincent, Howe, Nicole, Warshamanage, Rangana, Weinert, Tobias, Panepucci, Ezequiel, Vogeley, Lutz, Basu, Shibom, Diederichs, Kay, Caffrey, Martin, Wang, Meitian
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6123769/
https://ncbi.nlm.nih.gov/pubmed/30272004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-018-0123-6
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