Engineered bidirectional promoters enable rapid multi-gene co-expression optimization

Numerous synthetic biology endeavors require well-tuned co-expression of functional components for success. Classically, monodirectional promoters (MDPs) have been used for such applications, but MDPs are limited in terms of multi-gene co-expression capabilities. Consequently, there is a pressing ne...

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Publicat a:Nat Commun
Autors principals: Vogl, Thomas, Kickenweiz, Thomas, Pitzer, Julia, Sturmberger, Lukas, Weninger, Astrid, Biggs, Bradley W., Köhler, Eva-Maria, Baumschlager, Armin, Fischer, Jasmin Elgin, Hyden, Patrick, Wagner, Marlies, Baumann, Martina, Borth, Nicole, Geier, Martina, Ajikumar, Parayil Kumaran, Glieder, Anton
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6123417/
https://ncbi.nlm.nih.gov/pubmed/30181586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05915-w
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