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The altered PD-1/PD-L1 pathway delivers the ‘one-two punch’ effects to promote the Treg/Th17 imbalance in pre-eclampsia

The programmed cell death-1 (PD-1)/PD-ligand 1 (PD-L1) pathway is critical for normal pregnancy by promoting regulatory T (Treg) cell development and inhibiting the Th17 response. However, the relationship between the PD-1/PD-L1 pathway and the Treg/Th17 imbalance in pre-eclampsia (PE) is an enigma....

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Bibliografiske detaljer
Udgivet i:Cell Mol Immunol
Main Authors: Zhang, Yonghong, Liu, Zhaozhao, Tian, Mei, Hu, Xiaohui, Wang, Liling, Ji, Jinlu, Liao, Aihua
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6123412/
https://ncbi.nlm.nih.gov/pubmed/28890543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2017.70
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