Chronic Stress Produces Persistent Increases in Plasma Corticosterone, Reductions in Brain and Cardiac Nitric Oxide Production, and Delayed Alterations in Endothelial Function in Young Prehypertensive Rats

This study was designed to investigate whether oxidative stress, nitric oxide (NO) deficiency and/or endothelial dysfunction (ED) are present in young borderline hypertensive rats (BHR) and whether these pathologies can be causally involved in the initiation of blood pressure (BP) increases. Additio...

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Bibliographic Details
Published in:Front Physiol
Main Authors: Bernatova, Iveta, Puzserova, Angelika, Balis, Peter, Sestakova, Natalia, Horvathova, Martina, Kralovicova, Zuzana, Zitnanova, Ingrid
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2018
Subjects:
Physiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6123386/
https://ncbi.nlm.nih.gov/pubmed/30210360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.01179
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