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Dysregulation of Astrocytic HMGB1 Signaling in Amyotrophic Lateral Sclerosis

Astrocytes have emerged as critical elements for the maintenance and function of the central nervous system. The expression on their cell membrane of RAGE and TLR4 receptors makes astrocytes susceptible to High-mobility group box 1 (HMGB1), a nuclear protein typically released in the extracellular m...

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Dades bibliogràfiques
Publicat a:Front Neurosci
Autors principals: Brambilla, Liliana, Martorana, Francesca, Guidotti, Giulia, Rossi, Daniela
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6123379/
https://ncbi.nlm.nih.gov/pubmed/30210286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2018.00622
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