LPS inactivation by a host lipase allows lung epithelial cell sensitization for allergic asthma

Allergic asthma is a chronic inflammatory disease primarily mediated by Th2 immune mechanisms. Numerous studies have suggested that early life exposure to lipopolysaccharide (LPS) is negatively associated with allergic asthma. One proposed mechanism invokes desensitization of lung epithelial cells b...

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Publicado en:J Exp Med
Autores principales: Qian, Guojun, Jiang, Wei, Zou, Benkun, Feng, Jintao, Cheng, Xiaofang, Gu, Jie, Chu, Tianqing, Niu, Chen, He, Rui, Chu, Yiwei, Lu, Mingfang
Formato: Artigo
Lenguaje:Inglês
Publicado: Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6122967/
https://ncbi.nlm.nih.gov/pubmed/30021797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20172225
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