The human CIB1–EVER1–EVER2 complex governs keratinocyte-intrinsic immunity to β-papillomaviruses

Patients with epidermodysplasia verruciformis (EV) and biallelic null mutations of TMC6 (encoding EVER1) or TMC8 (EVER2) are selectively prone to disseminated skin lesions due to keratinocyte-tropic human β-papillomaviruses (β-HPVs), which lack E5 and E8. We describe EV patients homozygous for null...

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Bibliografiske detaljer
Udgivet i:J Exp Med
Main Authors: de Jong, Sarah Jill, Créquer, Amandine, Matos, Irina, Hum, David, Gunasekharan, Vignesh, Lorenzo, Lazaro, Jabot-Hanin, Fabienne, Imahorn, Elias, Arias, Andres A., Vahidnezhad, Hassan, Youssefian, Leila, Markle, Janet G., Patin, Etienne, D’Amico, Aurelia, Wang, Claire Q.F., Full, Florian, Ensser, Armin, Leisner, Tina M., Parise, Leslie V., Bouaziz, Matthieu, Maya, Nataly Portilla, Cadena, Xavier Rueda, Saka, Bayaki, Saeidian, Amir Hossein, Aghazadeh, Nessa, Zeinali, Sirous, Itin, Peter, Krueger, James G., Laimins, Lou, Abel, Laurent, Fuchs, Elaine, Uitto, Jouni, Franco, Jose Luis, Burger, Bettina, Orth, Gérard, Jouanguy, Emmanuelle, Casanova, Jean-Laurent
Format: Artigo
Sprog:Inglês
Udgivet: Rockefeller University Press 2018
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Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6122964/
https://ncbi.nlm.nih.gov/pubmed/30068544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20170308
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