Co-delivery of ciprofloxacin and colistin in liposomal formulations with enhanced in vitro antimicrobial activities against multidrug resistant Pseudomonas aeruginosa

PURPOSE: This study aims to develop liposomal formulations containing synergistic antibiotics of colistin and ciprofloxacin for the treatment of infections caused by multidrug-resistant Pseudomonas aeruginosa. METHODS: Colistin (Col) and ciprofloxacin (Cip) were co-encapsulated in anionic liposomes...

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Publié dans:Pharm Res
Auteurs principaux: Wang, Shaoning, Yu, Shihui, Lin, Yuwei, Zou, Peizhi, Chai, Guihong, Yu, Heidi H, Wickremasinghe, Hasini, Shetty, Nivedita, Ling, Junhong, Li, Jian, Zhou, Qi (Tony)
Format: Artigo
Langue:Inglês
Publié: 2018
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6122860/
https://ncbi.nlm.nih.gov/pubmed/30094660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-018-2464-8
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