NLRC3 negatively regulates CD4(+) T cells and impacts protective immunity during Mycobacterium tuberculosis infection

NLRC3, a member of the NLR family, has been reported as a negative regulator of inflammatory signaling pathways in innate immune cells. However, the direct role of NLRC3 in modulation of CD4(+) T-cell responses in infectious diseases has not been studied. In the present study, we showed that NLRC3 p...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Hu, Shengfeng, Du, Xialin, Huang, Yulan, Fu, Yuling, Yang, Yalong, Zhan, Xiaoxia, He, Wenting, Wen, Qian, Zhou, Xinying, Zhou, Chaoying, Zhong, Xiao-Ping, Yang, Jiahui, Xiong, Wenjing, Wang, Ruining, Gao, Yuchi, Ma, Li
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6122840/
https://ncbi.nlm.nih.gov/pubmed/30133544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007266
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