Maintenance of low inflammation level by the ZFHX3 SNP rs2106261 minor allele contributes to reduced atrial fibrillation recurrence after pulmonary vein isolation

INTRODUCTION: The single nucleotide polymorphism (SNP) rs2106261 in the transcription factor gene ZFHX3 (16q22), a major regulator of inflammation, has been reported linking to atrial fibrillation (AF) by genome-wide association studies. Inflammation is known to be a strong predictor of atrial fibri...

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Vydáno v:PLoS One
Hlavní autoři: Tomomori, Shunsuke, Nakano, Yukiko, Ochi, Hidenori, Onohara, Yuko, Sairaku, Akinori, Tokuyama, Takehito, Motoda, Chikaaki, Matsumura, Hiroya, Amioka, Michitaka, Hironobe, Naoya, Ookubo, Yousaku, Okamura, Shou, Kawazoe, Hiroshi, Chayama, Kazuaki, Kihara, Yasuki
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6122824/
https://ncbi.nlm.nih.gov/pubmed/30180182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0203281
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