Increased DNA methylation variability in rheumatoid arthritis-discordant monozygotic twins

BACKGROUND: Rheumatoid arthritis is a common autoimmune disorder influenced by both genetic and environmental factors. Epigenome-wide association studies can identify environmentally mediated epigenetic changes such as altered DNA methylation, which may also be influenced by genetic factors. To inve...

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Udgivet i:Genome Med
Main Authors: Webster, Amy P., Plant, Darren, Ecker, Simone, Zufferey, Flore, Bell, Jordana T., Feber, Andrew, Paul, Dirk S., Beck, Stephan, Barton, Anne, Williams, Frances M. K., Worthington, Jane
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6122744/
https://ncbi.nlm.nih.gov/pubmed/30176915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-018-0575-9
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