PHF8 upregulation contributes to autophagic degradation of E-cadherin, epithelial-mesenchymal transition and metastasis in hepatocellular carcinoma

BACKGROUND: Plant homeodomain finger protein 8 (PHF8) serves an activator of epithelial-mesenchymal transition (EMT) and is implicated in various tumors. However, little is known about PHF8 roles in hepatocellular carcinoma (HCC) and regulating E-cadherin expression. METHODS: PHF8 expression pattern...

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Veröffentlicht in:J Exp Clin Cancer Res
Hauptverfasser: Zhou, Wuhua, Gong, Li, Wu, Qinchuan, Xing, Chunyang, Wei, Bajin, Chen, Tianchi, Zhou, Yuan, Yin, Shengyong, Jiang, Bin, Xie, Haiyang, Zhou, Lin, Zheng, Shusen
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6122561/
https://ncbi.nlm.nih.gov/pubmed/30180906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-018-0890-4
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