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Resistance of Leishmania infantum to allopurinol is associated with chromosome and gene copy number variations including decrease in the S-adenosylmethionine synthetase (METK) gene copy number

Leishmania infantum is one of the causative agents of visceral leishmaniasis (VL), a widespread, life-threatening disease. This parasite is responsible for the majority of human VL cases in Brazil, the Middle East, China, Central Asia and the Mediterranean basin. Its main reservoir are domestic dogs...

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Detalhes bibliográficos
Publicado no:Int J Parasitol Drugs Drug Resist
Main Authors: Yasur-Landau, Daniel, Jaffe, Charles L., David, Lior, Doron-Faigenboim, Adi, Baneth, Gad
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6122375/
https://ncbi.nlm.nih.gov/pubmed/30173105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpddr.2018.08.002
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