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DNA hypermethylation-mediated downregulation of antioxidant genes contributes to the early onset of cataracts in highly myopic eyes

High myopia is recognized as a risk factor for earlier onset of nuclear cataracts. One possible explanation for this is that lenses in highly myopic eyes are exposed to higher levels of oxygen than normal eyes owing to earlier vitreous liquefaction and, hence, are subjected to oxidative insults. Her...

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Bibliografiske detaljer
Udgivet i:Redox Biol
Main Authors: Zhu, Xiangjia, Li, Dan, Du, Yu, He, Wenwen, Lu, Yi
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6122317/
https://ncbi.nlm.nih.gov/pubmed/30172102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2018.08.012
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