RBM38 plays a tumor-suppressor role via stabilizing the p53-mdm2 loop function in hepatocellular carcinoma

BACKGROUND: Misregulation of the p53-mdm2 loop function is a major mechanism to promote hepatocellular carcinoma (HCC). RBM38, a member of the RNA recognition motif (RRM) family of RNA binding proteins (RBPs), plays a fundamental role in the posttranscriptional control of gene expression and regulat...

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Bibliographic Details
Published in:J Exp Clin Cancer Res
Main Authors: Ye, Jiazhou, Liang, Rong, Bai, Tao, Lin, Yan, Mai, Rongyun, Wei, Meng, Ye, Xinqin, Li, Lequn, Wu, Feixiang
Format: Artigo
Language:Inglês
Published: BioMed Central 2018
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6122209/
https://ncbi.nlm.nih.gov/pubmed/30176896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-018-0852-x
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