Early Developmental Exposure to General Anesthetic Agents in Primary Neuron Culture Disrupts Synapse Formation via Actions on the mTOR Pathway

Human epidemiologic studies and laboratory investigations in animal models suggest that exposure to general anesthetic agents (GAs) have harmful effects on brain development. The mechanism underlying this putative iatrogenic condition is not clear and there are currently no accepted strategies for p...

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Foilsithe in:Int J Mol Sci
Main Authors: Xu, Jing, Mathena, R. Paige, Xu, Michael, Wang, YuChia, Chang, CheJui, Fang, Yiwen, Zhang, Pengbo, Mintz, C. David
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2018
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6121894/
https://ncbi.nlm.nih.gov/pubmed/30049952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19082183
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