HER2 Heterogeneity Is Associated with Poor Survival in HER2-Positive Breast Cancer

Intratumoral human epidermal growth factor receptor 2 (HER2) heterogeneity has been reported in 16–36% of HER2-positive breast cancer and its clinical impact is under discussion. We examined the biological effects of HER2-heterogeneity on mouse models and analyzed metastatic brains by RNA sequence a...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Hosonaga, Mari, Arima, Yoshimi, Sampetrean, Oltea, Komura, Daisuke, Koya, Ikuko, Sasaki, Takashi, Sato, Eiichi, Okano, Hideyuki, Kudoh, Jun, Ishikawa, Shumpei, Saya, Hideyuki, Ishikawa, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6121890/
https://ncbi.nlm.nih.gov/pubmed/30042341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19082158
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