Stress-Induced Phosphorylation of Nuclear YB-1 Depends on Nuclear Trafficking of p90 Ribosomal S6 Kinase

Ionizing radiation (IR) and epidermal growth factor (EGF) stimulate Y-box binding protein-1 (YB-1) phosphorylation at Ser-102 in KRAS wild-type (KRASwt) cells, whereas in KRAS mutated (KRASmut) cells, YB-1 is constitutively phosphorylated, independent of IR or EGF. YB-1 activity stimulates the repai...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Tiwari, Aadhya, Rebholz, Simone, Maier, Eva, Dehghan Harati, Mozhgan, Zips, Daniel, Sers, Christine, Rodemann, H. Peter, Toulany, Mahmoud
Format: Artigo
Language:Inglês
Published: MDPI 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6121600/
https://ncbi.nlm.nih.gov/pubmed/30126195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19082441
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