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The Regulation and Function of the L-Type Amino Acid Transporter 1 (LAT1) in Cancer

The progression of cancer is associated with increases in amino acid uptake by cancer cells. Upon their entry into cells through specific transporters, exogenous amino acids are used to synthesize proteins, nucleic acids and lipids and to generate ATP. The essential amino acid leucine is also import...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Salisbury, Travis B, Arthur, Subha
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6121554/
https://ncbi.nlm.nih.gov/pubmed/30103560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19082373
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