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β-adrenergic Receptor Stimulation Revealed a Novel Regulatory Pathway via Suppressing Histone Deacetylase 3 to Induce Uncoupling Protein 1 Expression in Mice Beige Adipocyte

Browning of adipose tissue has been prescribed as a potential way to treat obesity, marked by the upregulation of uncoupling protein 1 (Ucp1). Several reports have suggested that histone deacetylase (HDAC) might regulate Ucp1 by remodelling chromatin structure, although the mechanism remains unclear...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Yuliana, Ana, Jheng, Huei-Fen, Kawarasaki, Satoko, Nomura, Wataru, Takahashi, Haruya, Ara, Takeshi, Kawada, Teruo, Goto, Tsuyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6121552/
https://ncbi.nlm.nih.gov/pubmed/30126161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19082436
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