NOX Inhibition Improves β-Adrenergic Stimulated Contractility and Intracellular Calcium Handling in the Aged Rat Heart

Cardiac aging is characterized by alterations in contractility and intracellular calcium ([Ca(2+)](i)) homeostasis. It has been suggested that oxidative stress may be involved in this process. We and others have reported that in cardiomyopathies the NADPH oxidase (NOX)-derived superoxide is increase...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Valdés, Álvaro, Treuer, Adriana V., Barrios, Guillermo, Ponce, Nikol, Fuentealba, Roberto, Dulce, Raul A., González, Daniel R.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6121436/
https://ncbi.nlm.nih.gov/pubmed/30111689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19082404
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