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The Timing of Melatonin Administration Is Crucial for Its Antidepressant-Like Effect in Mice
Melatonin is synthesized by the pineal gland with a circadian rhythm in synchrony with the environmental light/dark cycle. A gradual increase in circulating levels of melatonin occur after lights off, reaching its maximum around the middle of the dark phase. Agonists of melatonin receptors have prov...
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| Pubblicato in: | Int J Mol Sci |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
MDPI
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6121277/ https://ncbi.nlm.nih.gov/pubmed/30081472 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19082278 |
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