The Efficacy of Amifostine against Multiple-Dose Doxorubicin-Induced Toxicity in Rats

Amifostine is well known cytoprotector which is efficient when administered before a wide range of antineoplastic agents. The aim of our study was to investigate amifostine effects on doxorubicin-induced toxic changes in rats. Amifostine (75 mg/kg ip) was given 30 min before each dose of doxorubicin...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Jaćević, Vesna, Dragojević-Simić, Viktorija, Tatomirović, Željka, Dobrić, Silva, Bokonjić, Dubravko, Kovačević, Aleksandra, Nepovimova, Eugenie, Vališ, Martin, Kuča, Kamil
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6121234/
https://ncbi.nlm.nih.gov/pubmed/30103540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19082370
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