Profiling the Tumour Immune Microenvironment in Pancreatic Neuroendocrine Neoplasms with Multispectral Imaging Indicates Distinct Subpopulation Characteristics Concordant with WHO 2017 Classification

We successfully determined the difference of immune microenvironments between pNENs and pancreatic ductal adenocarcinomas (PDACs), and the histology-dependent variability among pNENs using multispectral fluorescent imaging system. Tumour tissue samples including 52 pNENs and 18 PDACs were investigat...

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Udgivet i:Sci Rep
Main Authors: Takahashi, Daigoro, Kojima, Motohiro, Suzuki, Toshihiro, Sugimoto, Motokazu, Kobayashi, Shin, Takahashi, Shinichiro, Konishi, Masaru, Gotohda, Naoto, Ikeda, Masafumi, Nakatsura, Tetsuya, Ochiai, Atsushi, Nagino, Masato
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6120899/
https://ncbi.nlm.nih.gov/pubmed/30177687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-31383-9
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