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A TGF-β1 genetic variant at the miRNA187 binding site significantly modifies risk of HPV16-associated oropharyngeal cancer

TGF-β1rs1982073 polymorphism at the miRNA-187 binding site may alter TGF-β1 expression and function, and thereby this polymorphism (genotype CT/CC) increases cancer susceptibility. HPV16 L1 seropositivity is associated with the risk of oral squamous cell carcinoma (OSCC), including oropharyngeal squ...

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Detalhes bibliográficos
Publicado no:Int J Cancer
Main Authors: Tao, Ye, Sturgis, Erich M., Huang, Zhigang, Sun, Yan, Dahlstrom, Kristina R., Wei, Qingyi, Li, Guojun
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6120756/
https://ncbi.nlm.nih.gov/pubmed/29663347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.31530
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