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A metallo pro-drug to target Cu(II) in the context of Alzheimer’s disease
Alzheimer’s disease and oxidative stress are connected. In the present communication, we report the use of a Mn(II)-based superoxide dismutase mimic ([Mn(II)(L)](+), 1(+)) as a pro-drug candidate to target Cu(II) associated events, i.e. Cu(II)-induced formation of reactive oxygen species (ROS) and m...
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| Publicado no: | Chemistry |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6120673/ https://ncbi.nlm.nih.gov/pubmed/29334419 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201706049 |
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